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991.
Crncević-Orlić Z Ruzić A Miletić B Petrović O Zaputović L Kehler T Racki S Kapović M 《Collegium antropologicum》2007,31(3):771-774
Gestational diabetes mellitus is a carbohydrate intolerance recognized in pregnancy. The objective of this study was to determine the prevalence of gestational diabetes mellitus (GDM) of all deliveries at the University Hospital Rijeka, Croatia (34 997 deliveries over 10-year period) using 2-hour 75 g oral glucose tolerant test and to evaluate the impact of GDM on neonatal outcomes and mother's health. Gestational diabetes was diagnosed in 55 of 128 pregnant women with suspected glucose intolerance. Logistic regression analysis was used to examine the relationship between fasting plasma glucose, age, family history, body mass index, maternal weight gain, neonatal weight, neonatal head diameter and Apgar score in the gestational diabetes group and in the non-diabetes group. The results indicate that fasting plasma glucose greater than 7.0 mmol/L and maternal overweight are strong predictors for GDM and macrosomia. There was no difference in the mode of delivery, and vitality and metabolic complications among the infants of all analyzed mothers. We concluded that to prevent GDM as well as to reduce the rate of macrosomic infants good glycemic control should be initiated as soon as possible. The 2-hour 75 g OGTT is worth enough to evaluate GDM. Women should be counseled and encouraged to lose weight before or at the beginning of the conception period. 相似文献
992.
In this report, four Bacillus strains were tested for effects on plant fitness and disease protection of oilseed rape (Brassica napus). The strains belonged to newly discovered plant-associated Bacillus amyloliquefaciens and a recently proposed species, Bacillus endophyticus. The fungal pathogens tested represented different infection strategies and included Alternaria brassicae, Botrytis cinerea, Leptosphaeria maculans, and Verticillium longisporum. The B. amyloliquefaciens strains showed no or a weak plant growth promoting activity, whereas the B. endophyticus strain had negative effects on the plant as revealed by phenological analysis. On the other hand, two of the B. amyloliquefaciens strains conferred protection of oilseed rape toward all pathogens tested. In vitro experiments studying the effects of Bacillus exudates on fungal growth showed clear growth inhibition in several but not all cases. The protective effects of Bacillus can therefore, at least in part, be explained by production of antibiotic substances, but other mechanisms must also be involved
probably as a result of intricate plant–bacteria interaction. The protective effects observed for certain Bacillus strains make them highly interesting for further studies as biocontrol agents in Brassica cultivation. 相似文献
993.
Sitnikova Tatiana Ya. Naumova Tatiana V. Mekhanikova Irina V. Kiyashko Sergey I. Kalmychkov Gennady V. Karanovic Ivana Zakharenko Alexandra S. Bukin Yuri S. Khabuev Andrey V. Ivanov Vyacheslav G. Khlystov Oleg M. Zemskaya Tamara I. 《Hydrobiologia》2022,849(8):1947-1968
Hydrobiologia - The biological traits of invertebrates inhabiting freshwater methane seeps are poorly understood. We analysed the relationship between invertebrate abundance and environmental... 相似文献
994.
Biochemistry (Moscow) - This review is focused on biology of genes encoding ribosomal RNA (rRNA) in mammals. rRNA is a structural component of the most abundant cellular molecule, the ribosome.... 相似文献
995.
Kondakova Olga A. Evtushenko Ekaterina A. Baranov Oleg A. Nikitin Nikolai A. Karpova Olga V. 《Biochemistry. Biokhimii?a》2022,87(6):548-558
Biochemistry (Moscow) - Structurally modified virus particles can be obtained from the rod-shaped or filamentous virions of plant viruses and bacteriophages by thermal or chemical treatment. They... 相似文献
996.
997.
Petrov Yu. V. Bakharev N. N. Bulanin V. V. Gusev V. K. Kurskiev G. S. Martynov A. A. Medvedev S. Yu. Minaev V. B. Patrov M. I. Petrov A. V. Sakharov N. V. Shchegolev P. B. Telnova A. Yu. Tolstyakov S. Yu. Yashin A. Yu. 《Plasma Physics Reports》2019,45(8):723-731
Plasma Physics Reports - Results of experimental studies of toroidal Alfvén eigenmodes (TAEs) in the Globus-M spherical tokamak (R = 36 cm, a = 24 cm) are reported. The experiments were... 相似文献
998.
Yurii Kornii Svitlana Chumachenko Oleg Shablykin Mark N. Prichard Scott H. James Caroll Hartline Victor Zhirnov Volodymyr Brovarets 《化学与生物多样性》2019,16(10)
A series of novel 2‐oxoimidazolidine derivatives were synthesized and their antiviral activities against BK human polyomavirus type 1 (BKPyV) were evaluated in vitro. Bioassays showed that the synthesized compounds 1‐{[(4E)‐5‐(dichloromethylidene)‐2‐oxoimidazolidin‐4‐ylidene]sulfamoyl}piperidine‐4‐carboxylic acid ( 5 ) and N‐Cyclobutyl‐N′‐[(4E)‐5‐(dichloromethylidene)‐2‐oxoimidazolidin‐4‐ylidene]sulfuric diamide ( 4 ) exhibited moderate activities against BKPyV (EC50=5.4 and 5.5 μm , respectively) that are comparable to the standard drug Cidofovir. Compound 5 exhibited the same cytotoxicity in HFF cells and selectivity index (SI50) as Cidofovir. The selectivity index of compound 4 is three times less than that of Cidofovir due to the higher toxicity of this compound. Hence, these compounds may be taken as lead compound for further development of novel ant‐BKPyV agents. 相似文献
999.
Oleg. I. Artyushin Aleksandra A. Moiseeva Vladimir V. Zarubaev Aleksander V. Slita Anastasiya V. Galochkina Anna A. Muryleva Sophia S. Borisevich Olga I. Yarovaya Nariman F. Salakhutdinov Valery K. Brel 《化学与生物多样性》2019,16(11)
A series of camphecene and quinolizidine alkaloid (?)‐cytisine conjugates has been obtained for the first time using ‘click’ chemistry methodology. The cytotoxicity and virus‐inhibiting activity of compounds were determined against MDCK cells and influenza virus A/Puerto Rico/8/34 (H1N1), correspondingly, in in vitro tests. Based on the results obtained, values of 50 % cytotoxic dose (CC50), 50 % inhibition dose (IC50) and selectivity index (SI) were determined for each compound. It has been shown that the antiviral activity is affected by the length and nature of linkers between cytisine and camphor units. Conjugate 13 ((1R,5S)‐3‐(6‐{4‐[(2‐{(E)‐[(1R,4R)‐1,7,7‐trimethylbicyclo[2.2.1]heptan‐2‐ylidene]amino}ethoxy)methyl]‐1H‐1,2,3‐triazol‐1‐yl}hexyl)‐1,2,3,4,5,6‐hexahydro‐8H‐1,5‐methanopyrido[1,2‐a][1,5]diazocin‐8‐one), which contains cytisine fragment separated from triazole ring by –C6H12– aliphatic linker, showed the highest activity at relatively low toxicity (CC50=168 μmol, IC50=8 μmol, SI=20). Its selectivity index appeared higher than that of reference compound, rimantadine. According to theoretical calculations, the antiviral activity of the lead compound 13 can be explained by its influence on the functioning of neuraminidase. 相似文献
1000.
Ventrapati Pavan Kumar Andrew R. Supka Pierric Lemoine Oleg I. Lebedev Bernard Raveau Koichiro Suekuni Vivian Nassif Rabih Al Rahal Al Orabi Marco Fornari Emmanuel Guilmeau 《Liver Transplantation》2019,9(6)
The introduction of hexavalent T6+ cations in p‐type thermoelectric colusites Cu26T2Ge6S32 (T = Cr, Mo, W) leads to the highest power factors among iono‐covalent sulfides, ranging from 1.17 mW m?1 K?2 at 700 K for W to a value of 1.94 mW m?1 K?2 for Cr. In Cu26Cr2Ge6S32, ZT reaches values close to unity at 700 K. The improvement of the transport properties in these new sulfides is explained on the basis of electronic structure and transport calculations keeping in mind that the relaxation time is significantly influenced by the size and the electronegativity of the interstitial T cation. The rationale is based on the concept of a conductive “Cu–S” network, which in colusites corresponds to the more symmetric parent structure sphalerite. A detailed structural analysis of these colusites shows that the distortion of the conductive network is influenced by the presence in the structure of mixed octahedral–tetrahedral [TS4]Cu6 complexes where the T cations are underbonded to sulfur and form metal–metal interactions with copper, Cu–T distances decreasing from 2.76 Å for W to 2.71 Å for Cr. The interactions between these complexes are responsible for the outstanding electronic transport properties. By contrast, the thermal conductivity is not significantly affected. 相似文献